Projects

Project handled as Principal Investigator (PI) :

Completed :

1. Mathematical approaches to understand host-  pathogen cross-talk in Mycobacterial pathogenesis. (SERB, DST) (Principal Investigator)-- Completed in 2018.

2. Using genome scale metabolic models to identify novel host mediated therapies against Mycobacterium tuberculosis (THSTI intramural project) (Co-Principal Investigator)-- Completed in 2018.

3. A study to evaluate the association between air pollution and adverse pregnancy outcomes in a semi-urban district of North India. (THSTI intramural project). (Co-Principal Investigator)— Completed in 2019.

4. Unravelling the architecture of biological networks to identify points of sensitivity under perturbation. (DBT). (Project coordinator and PI) -- Completed in 2020.

5. Use of model trajectories to understand the regulatory mechanisms underlying metabolic diseases. (CSIR). (Principal investigator)-- Completed in 2020.

6. Improving the resolution of protein-protein interaction (PPI) network. (DBT). (Principal investigator)-- Completed in 2021.

7. Effect of time lag and stochastic perturbation on the calcium oscillation in cardiomyocyte: Study based on Mathematical model. (MATRICS, SERB, DST). (Principal Investigator)— Completed in 2022.

8. Understanding metabolic perturbation in cancer using mathematical models. (SERB, DST). (Principal Investigator)— Completed in 2022.

9. To study host cell regulation under influence of Mycobacterium tuberculosis using mathematical models. (DBT). (Principal Investigator)— Completed in 2023.

10. Investigating the effectiveness of autophagy as a potential target and a molecular signature of slow progressive diseases (Granted by THSTI intramural project). (Principal Investigator)— Completed in 2023.

Ongoing :

11. Building mathematical model for whole-body lipid metabolism (WBLM) to study non-alcoholic fatty liver disease (NAFLD) and use it to develop a general-purpose web-based application. (DBT). (Principal Investigator)— ongoing.

12. Unraveling fibrosis-dependent circular RNA and proteomic perturbations in pulmonary disease. (ICMR)(Principal Investigator)— ongoing.